High potency probiotics for pets.
Nowadays, more veterinarians are increasingly turning to probiotics to help pets with a variety of medical conditions. High potency probiotics for pets could help them restore the microbiome flora and control the "Dysbiosis."
The intestinal microbiome is the genome of all microbes inhabiting the gastrointestinal tract. Those microbes consist of viruses, bacteria, fungi, and protozoa. Bacteria represent the most abundant group within these microbes (Swanson et al., 2011). The intestine harbors approximately 100 trillion microbial cells, up to 10 times the number in the rest of the body. Consequently, microbial genes outnumber host genes, approximately tenfold (Honneffer et al., 2014). The canine and feline microbiome's composition and function and its crucial role in host health have garnered a lot of interest in recent years.
The intestinal microbiome fulfills various functions and, therefore, a balanced microbiome is essential for host health. In brief, the microbiota modulates the host immune system, protects the host from invading enteropathogens, and provides nutrients to the host by metabolizing and fermenting various dietary components. Cross-talk between intestinal microbiota and host immune cells is mediated either through microbial-derived metabolites or directly through bacterial surface molecules that activate receptors of the innate immune system (e.g., Toll-like receptors, NOD2 receptors) (Bansal et al., 2010). These metabolites can be either directly produced by bacteria (e.g., vitamins, short-chain fatty acids [SCFA]), or they are primary host metabolites that are converted through bacterial enzymes into secondary metabolites (e.g., conversion of primary to secondary bile acids).
The resident microbiota also constitutes an important part of the intestinal barrier by preventing pathogens' mucosal invasion through competition for nutrients and epithelial adhesion sites. It also contributes to a physiologically restrictive environment for nonresident bacterial species by secreting antimicrobial compounds and modulating luminal pH.
A physiological intestinal microbiome is crucial for host health. Thus, several studies showed that dogs with a gastrointestinal disease have alterations in their intestinal microbiome composition and diversity (Honneffer et al., 2014) (Markel, 2012) (Guard et al., 2015) (Suchodolski et al., 2012). "Dysbiosis" is the term that summarizes these alterations.
A high potency probiotics for pets add billions of beneficial live bacteria to the pets' microbiome. These good bacteria also help in many ways, including fighting off a surplus of bad bacteria to combat dysbiosis. Each capsule of Visbiome Vet contains 112.5 billion live colony-forming units (CFUs) of probiotic bacteria in defined ratios, the highest available concentration in the market.
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